March 22, 2022 – Khon Kaen University and Miss Lily came up with the Andrographolide Nano Emulsion technology for the first time in the world for industry scale. Assoc. Prof. Charnchai Panthongviriyakul, M.D., President of Khon Kaen University said, “Andrographolide are in trend applied in products in natural form, however, in the form of nano-emulsion products is another form that useful for various products.”

Prof. Monchai Duangchinda, Ph.D., Vice President for Research and Graduate Study of Khon Kaen University added, “Andrographolide is in the Diterpene Lactone group, which is an important active agent found in Andrographis paniculate. There are academic reports both in Thailand and abroad showing that it reduces fever, prevents inflammation, and resists viruses. As it is insoluble in water, therefore, in the form of nano-emulsion is now important” “The team has carried out research and development of the pure andrographolide product (>98%) using nano-emulsion technology – the first ever in the world for industry scale.”

Dr. Nopparat Intarawiset, the research leader of Miss Lily, Co. Ltd., said, “The nano-emulsion technology has been used in manufacturing a lot of products for a long time. These include cosmetics and medicine. However, andrographolide has never before been developed in this form. Nearly all research works have been on the medical benefits of powdered andrographolide. Nano emulsion in laboratories, in fact, faces a lot of difficulties, for example, uniformly downsizing the particles to less than 100 nanometers. In addition, the stability of the solution is hard to attain. The experiments require the right type and amount, while the pH value must be suitably adjusted to avoid oxidation, while acidity must be contained so that there will be no risk. Then the taste must be improved to lessen the bitterness of andrographolide so that it can be used by all age groups.”